A cure for your heart

Sorry if you thought this was an article to help with your love life. I have no skill in that department. Instead, if you have lived an unhealthy lifestyle, and your lipid profile (cholesterol, HDL, LDL and triglycerides) are out of range, sit up and take notice. I would still make the case that controlling your nutrition is an essential tool to change your lipid profile. In on own case, my HDL (good cholesterol) went from 35 to 80 due to diet. Often, medical intervention is equally important or even necessary.

Scientists have recently discovered an injectable antibody that lowers blood lipids. The discovery can potentially help the build-up of coronary heart diseases caused by the accumulation of fats, cholesterol and other harmful substance on the walls of your arteries. In case you don’t know, it is this that leads to a heart attack. In an article published in the New England Journal of Medicine, they reported that inhibiting the activity of ANGPTL3 in humans and mice by introducing something called evinacumab reduced triglycerides by seventy-six percent, and lowered LDL (bad cholesterol) by twenty-three percent. Also, it reversed the effects of atherosclerosis in rats.

Traditionally, a poor lipid profile has been dealt with by treating a patient with statins which often have not worked. Worse, the statins are unable to reverse any damage already done, and you carry the risk of any build up of plaque in your body.

Reported in people with a genetic mutation, ANGPTL3 has been studied in the past for people with liver and digestive problem. In such people, it was indicated that they also seemed to have an excellent lipid profile. Scientists are now attempting to recreate the same genetic mutation in regular folks like you and me. There is a blockbuster medicine coming soon for those at risk for cardiac ailments. In the meantime, do fix your nutrition habits anyways.


Ritesh is a born again health enthusiast and holds a Certificate in Physiology from Harvard Medical School and a Certificate in Nutrition from Tufts University.